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Scientists have spent many years working on the microbial ecology of the gastrointestinal tract, focusing on developing novel strategies for preventing the colonisation of the gut by pathogens.
FMT is a microbial therapy that delivers stool from a healthy person into the colon of a sick person. Explore a list of FMT FAQS which cover some of the most commonly asked questions about Gut Flora Transplants (FMT).
The Leading Advisory
Centre For FMT
Fecal microbiota transplantation (FMT) is the administration of a solution of fecal matter from a donor into the intestinal tract of a recipient in order to directly change the recipient’s gut microbial composition and provide a range of health benefits.
FMT is used for the treatment of gastrointestinal diseases such as inflammatory bowel disease, autoimmune enteropathy, and irritable bowel syndrome, clostridium difficile enteritis, etc. At the same time, it is also a new therapeutic research direction for diseases such as Parkinson’s disease, chronic fatigue syndrome, multiple sclerosis, obesity, metabolic syndrome and major depression.
Make an informed choice
During the past decade, FMT has transitioned from a low-tech procedure, sporadically used by clinicians who were committed to treating severely ill patients, to a safe and quality-audited routine treatment.
Our goal is to provide research, offer advice and information on all aspects of FMT, providing our users with the facts to make an informed choice.
qualities that mean you can place your trust in them.
Centre for Digestive Disease
Los Angeles Colon and Rectal Surgical Associates
Moonee Valley Specialist Centre
Dr. Jorge Chang Mayorga, Ciudad de Guatemala
Martin H Poleski, MD – Duke University School of Medicine
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The Safety of FMT for CDI in Immunocompromised Sufferers Patients
New research from the School of Medicine on fecal transplants benefiting patients with recurrent C. difficile infections
Efficacy of faecal microbiota transplantation for patients with IBS
Faecal microbiota transplant as a medicinal product for the treatment of Clostridioides difficile infection
The Potential of Microbiome Manipulation as a Therapeutic Strategy in Clostridium difficile Infection
Summary of FMT studies for recurrent Clostridium difficile infection
Development Process of Fecal Microbiota Transplantation
In July 2013, FDA (USA) issued a guidance document stating that it intends to exercise enforcement discretion under limited conditions regarding the IND requirements for the use of FMT products to treat C. difficile infection in patients that have not responded to standard therapies. This includes needing to prove 3 courses of vancomycin antibiotic have failed to bring the infection under control before FMT will be permitted on a licence-by-licence basis.
MHRA (UK) start to consider that as FMT is so effective against RCDI (Recurrent C. difficile Infection), it should come fully under their control and be classified as a medicine.
MHRA (UK) recognises the Good Manufacturing Process (GMP) for Birmingham University for production of FMT.
MHRA (UK) issues GMP certificate and licence to manufacture under a Specials Licence for Taymount Ltd (TML.science) UK. TML.science has produced over 42,000 implants without serious side effects.
FMT clinicians administer transplants direct to the colon, using a paediatric catheter to enhance client comfort. Patients report that the procedure is painless.
A few FMT researchers use a ‘top-down” process where a nasogastric tube is inserted and tracked down through the esophagus and stomach, sometimes into the duodenum.
For a number of reasons (which include client comfort) most practitioners prefer to use a rectal catheter infusion of the implant that delivers the transplanted gut flora directly to the large bowel (colon).
In UK law, only paediatricians with a current medical licence can treat children under the age of 16. Therefore, at present UK based clinics CANNOT accept children under the age of 16 as clients.
It is an emotive subject and we fully understand parents’ desperation when they contact us for advice.
FMT is still in a research phase and UK law has a strong view on parents who attempt a non-clinical and “experimental” treatment on a child.
Taymount Bahamas Clinic has a resident paediatrician and will consider clients between the ages of 5 and 18. Each case is considered on its own merit through consultation and of course, travel to The Bahamas is necessary for any FMT programmes offered.
Any UK NHS client wishing to have this treatment paid for by the NHS will have to directly approach their own doctor to ask if their area CCG – Clinical Commissioning Group (formerly called a PCT – Primary Care Trust) will fund their treatment from the local health budget.
No, not at all. We stress that FMT is not a replacement for any medical procedure whatsoever.
Clients should ALWAYS refer to their registered Medical Practitioner in the first instance and we recommend that medical advice be sought before booking or undertaking Faecal Microbiota Transplants (FMT).